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Meta-Analysis
. 2013 Oct 18;8(10):e77860.
doi: 10.1371/journal.pone.0077860. eCollection 2013.

Contrast sensitivity and spherical aberration in eyes implanted with AcrySof IQ and AcrySof Natural intraocular lens: the results of a meta-analysis

Jianping Liu  1 , Jiangyue Zhao, Liwei Ma, Guangcong Liu, Di Wu, Jinsong Zhang
Affiliations
Meta-Analysis

Contrast sensitivity and spherical aberration in eyes implanted with AcrySof IQ and AcrySof Natural intraocular lens: the results of a meta-analysis

Jianping Liu et al. PLoS One. .

Abstract

Background: To systematically evaluate the visual performance of aspheric AcrySof IQ and spherical AcrySof Natural intraocular lens (IOL) after cataract surgery.

Methodology/principal findings: Potential randomized controlled trials (RCTs) that involved implanting AcrySof IQ and AcrySof Natural were searched from PubMed, Web of science, EMBASE, Chinese Science and Technology Periodicals Databases and Cochrane Central Register of Controlled Trials. The methodological quality of the studies was assessed by the Jadad method. Standardized mean differences (SMDs) with 95% confidence intervals (CIs) of best-corrected visual acuity (BCVA), contrast sensitivity and spherical aberration were pooled using a random-effects model. Seven studies were identified and analyzed to compare AcrySof IQ (236 eyes) with AcrySof Natural (232 eyes) after phacoemulsification. There was no significant difference in postoperative BCVA between AcrySof IQ and AcrySof Natural (p =0.137) after a follow up of 3 months. For contrast sensitivity, these differences reached statistical significance under photopic conditions at two spatial frequencies (3 cycles per degree (cpd), 6 cpd, 12 cpd, and 18 cpd; p =0.022, p =0.017, p = 0.065, and p=0.191, respectively) and under mesopic conditions at three spatial frequencies (3 cpd, 6 cpd, 12 cpd, and 18 cpd; p =0.007, p =0.033, p =0.030, and p =0.080, respectively). Eyes with AcrySof IQ also had statistically significant less spherical aberration than eyes with AcrySof Natural (p<0.001). Sensitivity analysis showed that the results were relatively stable and reliable.

Conclusions/significance: The overall findings indicate that AcrySof IQ with a modified aspheric surface induced significantly less spherical aberration than AcrySof Natural. Contrast sensitivity in eyes with AcrySof IQ is better than that in eyes with AcrySof Natural, especially under mesopic conditions.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Standardized mean difference (SMD) in best-corrected visual acuity (BCVA): This forest plot showed the SMD in BCVA (log MAR) along with associated 95% confidence interval (CI), comparing AcrySof IQ and AcrySof Natural intraocular lens.
Figure 2
Figure 2. Standardized mean difference (SMD) in contrast sensitivity: This forest plot showed the SMD in postoperative contrast sensitivity under photopic conditions at 3 cycles per degree (cpd), 6 cpd, 12 cpd, and 18 cpd along with associated 95% confidence interval (CI), comparing AcrySof IQ and AcrySof Natural intraocular lens.
Figure 3
Figure 3. Standardized mean difference (SMD) in contrast sensitivity: This forest plot showed the SMD in postoperative contrast sensitivity under mesopic conditions at 3 cycles per degree ( cpd ), 6 cpd, 12 cpd, and 18 cpd along with associated 95% confidence interval (CI), comparing AcrySof IQ and AcrySof Natural intraocular lens.
Figure 4
Figure 4. Standardized mean difference (SMD) in spherical aberration: This forest plot showed the SMD in spherical aberration along with associated 95% confidence interval (CI), comparing AcrySof IQ and AcrySof Natural intraocular lens.
Figure 5
Figure 5. Funnel plot for the results between AcrySof IQ and AcrySof Natural intraocular lens.
Egger’ publication bias test result (p =0.476).
See this image and copyright information in PMC

References

    1. Resnikoff S, Pascolini D, Etya’ale D, Kocur I, Pararajasegaram R, et al. (2004) Global data on visual impairment in the year 2002. Bull World Health Organ 82: 844-851. - PMC - PubMed
    1. Pesudovs K, Dietze H, Stewart OG, Noble BA, Cox MJ et al. (2005) Effect of cataract surgery incision location and intraocular lens type on ocular aberrations. J Cataract Refract Surg 31: 725–734. doi:10.1016/j.jcrs.2004.09.028. PubMed: 15899449. - DOI - PubMed
    1. Elliott DB (1993) Evaluating visual function in cataract. Optom Vis Sci 70: 896–902. doi:10.1097/00006324-199311000-00006. PubMed: 8302525. - DOI - PubMed
    1. Olawoye O, Ashaye A, Bekibele C, Ajuwon AJ (2012) Quality-of-Life and Visual Function after Manual Small Incision Cataract Surgery in South Western Nigeria .West Afr J Med 31: 114-119. PubMed: 23208481. - PubMed
    1. Ginsburg AP, Evans DW, Sekule R, Harp SA (1982) Contrast sensitivity predicts pilots’ performance in aircrafts simulators. Am J Optom Physiol Opt 59: 105-109. doi:10.1097/00006324-198201000-00020. PubMed: 7055195. - DOI - PubMed

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