m(6)A mRNA methylation: a new circadian pacesetter
- PMID: 24209613
- DOI: 10.1016/j.cell.2013.10.028
m(6)A mRNA methylation: a new circadian pacesetter
Abstract
The purpose of m(6)A methylation of RNA, first observed in the 1970s, has been a longstanding mystery. Fustin et al. now show that it regulates RNA processing and determines the period and oscillatory stability of the mammalian circadian clockwork.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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RNA-methylation-dependent RNA processing controls the speed of the circadian clock.Cell. 2013 Nov 7;155(4):793-806. doi: 10.1016/j.cell.2013.10.026. Cell. 2013. PMID: 24209618
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