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Editorial
. 2013 Dec 10;81(24):2064-5.
doi: 10.1212/01.wnl.0000437310.96160.fa. Epub 2013 Nov 8.

Spice, pot, and stroke

John C M Brust  1
Affiliations
Editorial

Spice, pot, and stroke

John C M Brust. Neurology. .

Abstract

The endocannabinoid system includes 2 types of G-protein coupled receptors: CB1 (mostly in the brain) and CB2 (in peripheral lymphoid tissue). The major cannabinoid ligands are arachidonylethanolamine ("anandamide," the Sanskrit word for bliss) and 2-arachidonylglycerol ("2AG"). It is by binding to CB1 receptors that δ-9-tetrahydrocannabinol (THC), the principal psychoactive ingredient in marijuana ("pot"), produces its intended subjective effects.

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  • Spice, pot, and stroke.
    Barber PA, Anderson NE, Brust JC. Barber PA, et al. Neurology. 2014 Aug 19;83(8):772. doi: 10.1212/WNL.0000000000000722. Neurology. 2014. PMID: 25135912 No abstract available.
  • Author response.
    Brust JC. Brust JC. Neurology. 2014 Aug 19;83(8):772. Neurology. 2014. PMID: 25275171 No abstract available.

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