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. 2013 Nov 8;3(11):e157.
doi: 10.1038/bcj.2013.54.

ASXL1, TP53 and IKZF3 mutations are present in the chronic phase and blast crisis of chronic myeloid leukemia

Affiliations

ASXL1, TP53 and IKZF3 mutations are present in the chronic phase and blast crisis of chronic myeloid leukemia

J Menezes et al. Blood Cancer J. .
No abstract available

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Figures

Figure 1
Figure 1
Mutational profile by whole-exome sequencing along the three phases of the index CML patient. (a) The Venn diagram representing the distribution of mutated genes in CML progression. (b) Frequencies of the mutant alleles of every affected gene at the three time points of CML progression. Sanger validation was conducted for those genes with frequencies above 20%: ZEB2, UBE2G2, TP53, TMEM57, IKZF3, C4BPA, ASXL1 and ADAMTS16.

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