Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Feb 1;152(2):304-7.
doi: 10.1016/0003-2697(86)90413-6.

Acceleration of nucleic acid hybridization rate by polyethylene glycol

R M Amasino

Acceleration of nucleic acid hybridization rate by polyethylene glycol

R M Amasino. Anal Biochem. .

Abstract

The addition of polyethylene glycol to filter-bound nucleic acid hybridization greatly increases the hybridization rate. With single-stranded probes, the increase obtained with polyethylene glycol is significantly greater than that obtained with dextran sulfate. Additionally, polyethylene glycol is easier to manipulate and less expensive than dextran sulfate.

PubMed Disclaimer

Publication types

LinkOut - more resources