Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014;23(2):170-3.
doi: 10.1159/000351577. Epub 2013 Nov 9.

A solitary fibrous tumour of the eyelid

Irene Pecorella  1 , Filippo Cruciani, Valeria Russo
Affiliations
Case Reports

A solitary fibrous tumour of the eyelid

Irene Pecorella et al. Med Princ Pract. 2014.

Abstract

Objective: To report a case of palpebral solitary fibrous tumour (SFT).

Clinical presentation and intervention: An elderly man presented with a slow-growing painless mass in the lower conjunctival fornix in the left eye. The lesion was excised and it measured 0.9 cm in maximum diameter. The microscopic features were characteristic of a benign SFT, with immunohistochemical reactivity for vimentin, CD34 and Bcl-2 protein. Nuclear staining for progesterone receptor was also observed.

Conclusion: This tumour displayed a benign course, with no recurrence after excision. CD34 immunohistochemistry proved to be a useful adjunct to the microscopic diagnosis.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Spindle- to ovoid-shaped cells interspersed with irregular vascular channels and ectatic or compressed, thin-walled vessels.
Fig. 2
Fig. 2
Strong positive immunolabelling (brown staining) of tumour cells is evident with both CD34 (a) and Bcl-2 (b). Bcl-2 protein is associated with prolonged cell survival due to inhibition of apoptosis. c Numerous tumour cell nuclei are immunostained for PR. Avidin-biotin-peroxidase-DAB. a ×100. b ×250. c ×400.
See this image and copyright information in PMC

References

    1. Klemperer P, Rabin CB. Primary neoplasms of the pleura: a report of five cases. Arch Pathol. 1931;11:385–412.
    1. Bongiovanni M, Viberti L, Pecchioni C, et al. Steroid hormone receptor in plural solitary fibrous tumours and CD34+ progenitor stromal cells. J Pathol. 2002;1982:252. - PubMed
    1. Furusato E, Valenzuela IA, Fanburg-Smith JC, et al. Orbital solitary fibrous tumor: encompassing terminology for hemangiopericytoma, giant cell angiofibroma, and fibrous histiocytoma of the orbit: reappraisal of 41 cases. Hum Pathol. 2011;42:120–128. - PubMed
    1. Heathcote GJ. Pathology update: solitary fibrous tumor of the orbit. Can J Ophthalmol. 1997;32:432–435. - PubMed
    1. Girnita L, Sahlin S, Orrego A, et al. Malignant solitary fibrous tumour of the orbit. Acta Ophthalmol. 2009;87:464–467. - PubMed

Publication types