Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 May;77(5):1712-5.
doi: 10.1172/JCI112491.

Infection of monocyte/macrophages by human T lymphotropic virus type III

D D Ho, T R Rota, M S Hirsch

Infection of monocyte/macrophages by human T lymphotropic virus type III

D D Ho et al. J Clin Invest. 1986 May.

Abstract

Normal blood-derived monocyte/macrophages were found to be susceptible to infection in vitro by human T lymphotropic virus type III (HTLV-III), the etiologic agent of the acquired immunodeficiency syndrome. In addition, HTLV-III was recovered from monocyte/macrophages of patients infected with this virus. The above findings raise the possibility that HTLV-III-infected monocyte/macrophages may serve as a vehicle for the dissemination of virus to target organs and as a reservoir for viral persistence, as has been shown for other lentiviruses including visna virus and caprine arthritis encephalitis virus.

PubMed Disclaimer

References

    1. J Immunol. 1980 Apr;124(4):1943-8 - PubMed
    1. AIDS Res. 1984-1985;1(6):447-54 - PubMed
    1. Science. 1983 May 20;220(4599):868-71 - PubMed
    1. Cell Immunol. 1983 May;78(1):83-99 - PubMed
    1. Science. 1984 May 4;224(4648):497-500 - PubMed

Publication types

MeSH terms

Substances