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Review
. 2013 Oct;50(10):939-49.
doi: 10.1007/s13312-013-0265-z.

Recent advances in management of bronchiolitis

Affiliations
Review

Recent advances in management of bronchiolitis

Nishant Verma et al. Indian Pediatr. 2013 Oct.

Abstract

Background: Bronchiolitis is one of the major causes for hospital admissions in infants. Managing bronchiolitis, both in the outpatient and inpatient setting remains a challenge to the treating pediatrician. The effectiveness of various interventions used for infants with bronchiolitis remains unclear.

Need and purpose: To evaluate the evidence supporting the use of currently available treatment and preventive strategies for infants with bronchiolitis and to provide practical guidelines to the practitioners managing children with bronchiolitis.

Methods: A search of articles published on bronchiolitis was performed using PubMed. The areas of focus were diagnosis, treatment and prevention of bronchiolitis in children. Relevant information was extracted from English language studies published over the last 20 years. In addition, the Cochrane Database of Systematic Reviews was searched.

Results and conclusions: Supportive care, comprising of taking care of oxygenation and hydration, remains the corner-stone of therapy in bronchiolitis. Pulse oximetry helps in guiding the need for oxygen administration. Several recent evidence-based reviews have suggested that bronchodilators or corticosteroids lack efficacy in bronchiolitis and should not be routinely used. A number of other novel therapies (such as nebulized hypertonic saline, heliox, CPAP, montelukast, surfactant, and inhaled furosemide) have been evaluated in clinical trials, and although most of them did not show any beneficial results, some like hypertonic saline, surfactant, CPAP have shown promising results.

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Comment in

  • Management of bronchiolitis.
    Sharma S. Sharma S. Indian Pediatr. 2014 Mar;51(3):235-6. doi: 10.1007/s13312-014-0362-7. Indian Pediatr. 2014. PMID: 24736923 No abstract available.
  • Author's reply: To PMID 24222284.
    Lodha R, Kabra SK. Lodha R, et al. Indian Pediatr. 2014 Mar;51(3):236. Indian Pediatr. 2014. PMID: 24851277 No abstract available.

References

    1. American Academy of Pediatrics Subcommittee on DiagnosisManagement of Bronchiolitis. Diagnosis and management of bronchiolitis. Pediatrics. 2006;118:1774–1793. doi: 10.1542/peds.2006-2223. - DOI - PubMed
    1. Hanson IC, Shearer WT. Bronchiolitis. In: McMillan JA, Feigin RD, DeAngelis C, Jones MD, editors. Oski’s Pediatrics: Principles and Practice. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 1391.
    1. Wright AL, Taussig LM, Ray CG, Harrison HR, Holberg CJ. The Tucson Children’s Respiratory Study II. Lower respiratory tract illness in the first year of life. Am J Epidemiol. 1989;129:1232–1264. - PubMed
    1. Gupta S, Shamsundar R, Shet A, Chawan R, Srinivasa H. Prevalence of respiratory syncytial virus infection among hospitalized children presenting with acute lower respiratory tract infections. Indian J Pediatr. 2011;78:1495–147. doi: 10.1007/s12098-011-0491-0. - DOI - PubMed
    1. Bharaj P, Sullender WM, Kabra SK, Mani K, Cherian J, Tyagi V, et al. Respiratory viral infections detected by multiplex PCR among pediatric patients with lower respiratory tract infections seen at an urban hospital in Delhi from 2005 to 2007. Virol J. 2009;26:89. doi: 10.1186/1743-422X-6-89. - DOI - PMC - PubMed

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