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. 2013:2013:493836.
doi: 10.1155/2013/493836. Epub 2013 Oct 7.

Primary ovarian large B-cell lymphoma

Mine Islimye Taskın  1 , Levent Gokgozoglu, Bedrı Kandemır
Affiliations

Primary ovarian large B-cell lymphoma

Mine Islimye Taskın et al. Case Rep Obstet Gynecol. 2013.

Abstract

The involvement of the ovary by malignant lymphoma is a well-known late manifestation of disseminated nodal disease. Primary ovarian lymphoma is rare. We herein describe a case of primary ovarian diffuse large B-cell lymphoma involving unilateral ovary in a 38-year-old woman which was detected incidentally. Preoperative ultrasonic imaging showed a 46∗42 mm heterogeneous cystic mass. Laparotomy revealed that left adnexal mass and left salpingo-oophorectomy was performed. The current diagnosis was determined after immunostaining. The patient was treated with R-CHOP regimen after the operation. She remains cancer-free 24 months after chemotherapy.

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Figures

Figure 1
Figure 1
Tumor cells infiltrating the ovarian tissue. Diffuse growth pattern of tumor cells (H&E, ×10 magnification).
Figure 2
Figure 2
Paraffin immunostaining studies showed strong positivity of the neoplastic cells for B-cell CD20.
Figure 3
Figure 3
Paraffin immunostaining studies showed strong positivity of the neoplastic cells for leucocyte commen antigen (LCA).
Figure 4
Figure 4
Immunostaining was negative for PLAP.
See this image and copyright information in PMC

References

    1. Yadav R, Sharma MC, Karak AK, Agarwal N, Kumar R, Kumar L. Natural history of primary precursor B lymphoblastic lymphoma of the ovary: report of a rare case. Journal of Obstetrics and Gynaecology Research. 2013;39(2):611–616. - PubMed
    1. Yildirim Y. Primary ovarian large B-cell lymphoma in patient with juvenile rheumatoid arthritis treated with low dose Methotrexate. Gynecologic Oncology. 2005;97(1):249–252. - PubMed
    1. Fox H, Langley FA, Govan ADT, Hill SA, Bennett MH. Malignant lymphoma presenting as an ovarian tumour: a clinicopathological analysis of 34 cases. British Journal of Obstetrics and Gynaecology. 1988;95(4):386–390. - PubMed
    1. Vang R, Medeiros LJ, Warnke RA, Higgins JP, Deavers MT. Ovarian non-Hodgkin’s lymphoma: a clinicopathologic study of eight primary cases. Modern Pathology. 2001;14(11):1093–1099. - PubMed
    1. Vang R, Medeiros LJ, Fuller GN, Sarris AH, Deavers M. Non-Hodgkin’s lymphoma involving the gynecologic tract: a review of 88 cases. Advances in Anatomic Pathology. 2001;8(4):200–217. - PubMed

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