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Case Reports
. 2013 Oct-Dec;98(4):315-8.
doi: 10.9738/INTSURG-D-13-00015.1.

A case of benign schwannoma of the ascending colon treated with laparoscopic-assisted wedge resection

Se-Jin Baek  1 , Won Hwangbo, Jin Kim, In-Sun Kim
Affiliations
Case Reports

A case of benign schwannoma of the ascending colon treated with laparoscopic-assisted wedge resection

Se-Jin Baek et al. Int Surg. 2013 Oct-Dec.

Abstract

Isolated colonic schwannomas are rare gastrointestinal mesenchymal tumors. Only a small number of cases have been reported. Occurrence of these tumors is more common in the stomach than in the large intestine. These spindle cell lesions are distinct from leiomyoma, leiomyosarcoma, and gastrointestinal stromal tumors because the tumor cells have a distinct immunophenotype, with strong diffuse positivity for S-100 and vimentin, as well as corroborative negative staining of CD117 and smooth muscle markers. We present a case of colonic schwannoma in a 70-year-old woman who had no specific symptoms. The patient was diagnosed with a submucosal tumor in the ascending colon on colonoscopy and abdominal computed tomography. Laparoscopic-assisted wedge resection of colon was performed. The very rare pathologic diagnosis of ascending schwannoma was made postoperatively. This case is interesting because schwannomas of the colon and rectum are extremely rare and are treated by laparoscopic-assisted wedge resection.

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Figures

Fig. 1
Fig. 1
Colonofiberscopic findings. There is a pedunculated mass measuring about 2 cm with a short, thick stalk and central ulceration at the mid ascending colon (arrow). Clipping was done for localization needed at operation.
Fig. 2
Fig. 2
Abdominal CT findings. A round polypoid lesion with homogeneous low attenuation inside was revealed in the ascending colon without adjacent wall thickening (arrow).
Fig. 3
Fig. 3
The tumor locates in the lamina propria and attaches to the muscularis propria. The tumor cells show nodular and fascicular arrangement of spindle cells in edematous stroma (a). The tumor cells show elongated and pointed nuclei (b).
Fig. 4
Fig. 4
The tumor cells are positive for S-100 protein (a) and CD34 (b), but they are negative for CD117 (c) and desmin (d; all ×10).
See this image and copyright information in PMC

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