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. 2013 Dec;14(12):1039-42.
doi: 10.1038/embor.2013.177. Epub 2013 Nov 15.

Complex diseases require complex therapies

Ravi Iyengar  1
Affiliations

Complex diseases require complex therapies

Ravi Iyengar. EMBO Rep. 2013 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

R.I. receives support for one postdoctoral position from GlaxoSmithKline (GSK). The person supported by GSK has had no role in this paper.

Figures

Figure 1
Figure 1
A schematic representation of the layers of networks that underlie organismal function, such as control of blood pressure (hypertension) or glucose levels in the blood (type 2 diabetes). Organismal functions arise from functional interactions between multiple organs. Organ and tissue functions arise from the functions of the multiple cell types of which they are comprised. Molecular networks exist within and between cell types that give rise to cellular functions. Drugs typically change the activity of the molecular components, and this change in activity percolates up to eventually affect organismal functions or malfunctions in disease states.
Figure 2
Figure 2
A flow chart of how systems biology can affect various facets of pharmacology and therapeutics.
None
Ravi Iyengar
See this image and copyright information in PMC

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