Primary structure of human salivary alpha-amylase gene
- PMID: 2423416
- DOI: 10.1016/0378-1119(86)90110-1
Primary structure of human salivary alpha-amylase gene
Abstract
A recombinant clone which covers the human salivary alpha-amylase gene in a single insert has been isolated from a human genomic DNA library using a human salivary alpha-amylase cDNA as a probe. Restriction mapping and nucleotide (nt) sequence analysis revealed that this gene is approx. 10 kb long and is separated into eleven exons by ten introns. Its 5'-flanking region has some sequence homology with that of mouse salivary alpha-amylase gene [Schibler et al., J. Mol. Biol. 155 (1982) 247-266].
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