Visual control of manual actions: brain mechanisms in typical development and developmental disorders

Abstract

Some key stages in the development of manual actions have been discussed in this supplement based on the idea of the dorsal cortical stream as the pathway for translating visual information into action control. We argue that visual information, transmitted through specialized visuomotor dorsal-stream modules, is required in the control of manual actions for selecting and attending to the target object of the action, translating visual spatial information into motor programmes and planning a coordinated sequence of actions so as to reach an optimal end-state. In typical development, we illustrate dorsal-stream processing through results on the use of stereoscopic information to guide infants' reaches, and changes in target selection and detailed kinematics of reaches depending on age, object size, and reaching in darkness (when dorsal-stream information rapidly decays). We hypothesize 'dorsal-stream vulnerability' as a widespread feature of neurodevelopmental disorders, such as autism, Williams syndrome, and children born very preterm. Such deficits, identified as abnormal visuomanual actions, are seen in bimanual coordination, visual guidance of action in the 'postbox' task, and failures in motor planning for end-state comfort. We discuss the possible application of these approaches to a wider range of disorders including developmental coordination disorder.