A sting in the tale of TH2 immunity
- PMID: 24238337
- DOI: 10.1016/j.immuni.2013.10.015
A sting in the tale of TH2 immunity
Abstract
Allergies are widely considered misguided Th2 cell responses. In this issue, Palm et al. (2013) and Marichal et al. (2013) show that mice mount anti-venom Th2 cell responses that share components of the "allergic" response but confer protection.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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A beneficial role for immunoglobulin E in host defense against honeybee venom.Immunity. 2013 Nov 14;39(5):963-75. doi: 10.1016/j.immuni.2013.10.005. Epub 2013 Oct 24. Immunity. 2013. PMID: 24210352 Free PMC article.
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Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity.Immunity. 2013 Nov 14;39(5):976-85. doi: 10.1016/j.immuni.2013.10.006. Epub 2013 Oct 24. Immunity. 2013. PMID: 24210353 Free PMC article.
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