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. 2013 Nov;58(6):492.
doi: 10.4103/0019-5154.119970.

Pseudoepitheliomatous keratotic and micaceous balanitis: a rare condition successfully treated with topical 5-Fluorouracil

Bangaru Hanumaiah  1 , Mohan, Nanjundaswamy Bisilavadi Lingaiah, Surendran Kalale Appaiah Kumaraswamy, B Vijaya
Affiliations

Pseudoepitheliomatous keratotic and micaceous balanitis: a rare condition successfully treated with topical 5-Fluorouracil

Bangaru Hanumaiah et al. Indian J Dermatol. 2013 Nov.

Abstract

A 50-year-old man presented with slow-growing dry, rough, micaceous scaly plaque over glans penis, which was compatible with clinical diagnosis of pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) and histologically suggestive of PKMB without cellular atypia. He was treated successfully with topical 5-fluorouracil with complete clearance of lesion in 3 weeks without recurrence for 10 months. PKMB is an extremely rare and interesting condition; only a handful cases have been reported in world literature.

Keywords: Carcinoma; micaceous scales; pseudoepitheliomatous hyperplasia.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Well-defined, dry, micaceous scaly plaque over the glans penis
Figure 2
Figure 2
Well-defined, dry, scaly plaque over the glans penis around the urethral orifice
Figure 3
Figure 3
Hyperkeratosis, parakeratosis, acanthosis with elongation of rete ridges (H and E, ×10)
Figure 4
Figure 4
Extensive parakeratosis and orthokeratosis (H and E, ×40)
Figure 5
Figure 5
Pronounced acanthosis (H and E, ×40)
Figure 6
Figure 6
Pronounced acanthosis without cytologic atypia (H and E, ×100)
Figure 7
Figure 7
Complete dissolution of keratotic scaly material in 10% KOH after 24 hours
Figure 8
Figure 8
Complete clearance of lesion, 3 weeks after topical 5-fluorouracil application
Figure 9
Figure 9
Complete clearance of lesion, 3 weeks after topical 5- fluorouracil application
See this image and copyright information in PMC

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