Topical-steroid-induced iatrogenic Cushing syndrome in the pediatric age group: A rare case report
- PMID: 24251179
- PMCID: PMC3830325
- DOI: 10.4103/2230-8210.119593
Topical-steroid-induced iatrogenic Cushing syndrome in the pediatric age group: A rare case report
Abstract
Cushing syndrome, a systemic disorder, is the result of abnormally high blood level of cortisol or other glucocorticoids. The most common cause of Cushing syndrome is prolonged exogenous administration of glucocorticoid hormones. Prolonged use of topical corticosteroids, particularly in children, may cause Cushing syndrome and suppression of the hypothalamopituitory-adrenal axis, which is less common than that of oral or parenteral route. However, iatrogenic Cushing syndrome in the infantile age group due to topical steroid is very rare and only a few patients have been reported to date in the literature. Here we report a case of iatrogenic Cushing syndrome due to topical steroid application in a 5-month-old female child admitted to the hospital for repeated episodes of fever and cough.
Keywords: Hypothalamopituitory axis; topical corticosteroid; İatrogenic Cushing's syndrome.
Conflict of interest statement
Figures
References
-
- Miller WL. The adrenal cortex and its disorders. In: Brook CG, Hindmarsh PC, editors. Clinical pediatric endocrinology. 4th ed. Oxford: Blackwell Science; 2001. pp. 321–76.
-
- Siklar Z, Bostancı I, Atli Ö, Dallar Y. An infantile Cushing syndrome due to misuse of topical steroid. Pediatr Dermatol. 2004;21:561–3. - PubMed
-
- West DP, Micali G. Principles of paediatric dermatological therapy. In: Harper J, Oranje A, Prose N, editors. Textbook of Pediatric Dermatology. 1st ed. London: Blackwell Science Ltd; 2000. pp. 1731–42.
-
- Bertrand J, Saez JM. Adrenal steroids: Biochemistry and physiology. In: Bertrand J, Rappaport R, Sizonenko PC, editors. Pediatric endocrinology. 2nd ed. Baltimore: Williams and Wilkins; 1993. pp. 283–304.
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
