Properties of monospecific antibodies to the glycoprotein of western equine encephalitis virus
- PMID: 2425229
- DOI: 10.1111/j.1348-0421.1986.tb00951.x
Properties of monospecific antibodies to the glycoprotein of western equine encephalitis virus
Erratum in
- Microbiol Immunol 1986;30(6):following 597
Abstract
Monospecific (MSp-) antisera against E1 and E2 glycoproteins of western equine encephalitis (WEE) virus were prepared and examined for binding activities to whole virions, hemagglutination-inhibition (HI), neutralization (NT) and protection. Both anti-E1 and anti-E2 MSp-Abs protected mice against WEE virus challenge. A competition experiment with monoclonal antibodies showed that these MSp-antisera appear to lack the antibody population for some epitopes involved in viral neutralization.
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