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. 1985 Aug;70(5):491-6.
doi: 10.1007/BF00305981.

A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients

W C Black 4th  1 , E S Krafsur
Affiliations

A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients

W C Black 4th et al. Theor Appl Genet. 1985 Aug.

Abstract

A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domestica L.) are included to illustrate features of the program.

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