Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Jan;42(Database issue):D191-8.
doi: 10.1093/nar/gkt1140. Epub 2013 Nov 18.

Activities at the Universal Protein Resource (UniProt)

UniProt Consortium
Collaborators

Activities at the Universal Protein Resource (UniProt)

UniProt Consortium. Nucleic Acids Res. 2014 Jan.

Abstract

The mission of the Universal Protein Resource (UniProt) (http://www.uniprot.org) is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequences and functional annotation. It integrates, interprets and standardizes data from literature and numerous resources to achieve the most comprehensive catalog possible of protein information. The central activities are the biocuration of the UniProt Knowledgebase and the dissemination of these data through our Web site and web services. UniProt is produced by the UniProt Consortium, which consists of groups from the European Bioinformatics Institute (EBI), the SIB Swiss Institute of Bioinformatics (SIB) and the Protein Information Resource (PIR). UniProt is updated and distributed every 4 weeks and can be accessed online for searches or downloads.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
UniProtKB manual and automatic biocuration processes.
Figure 2.
Figure 2.
Reference proteomes (excluding viruses) in UniProtKB.
See this image and copyright information in PMC

References

    1. Leinonen R, Diez FG, Binns D, Fleischmann W, Lopez R, Apweiler R. UniProt archive. Bioinformatics. 2009;20:3236–3237. - PubMed
    1. Suzek BE, Huang H, McGarvey P, Mazumder R, Wu CH. UniRef: comprehensive and non-redundant UniProt reference clusters. Bioinformatics. 2007;23:1282–1288. - PubMed
    1. Pruitt KD, Tatusova T, Maglott DR. NCBI reference sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res. 2007;37:D61–D65. - PMC - PubMed
    1. Brunak S, Danchin A, Hattori M, Nakamura H, Shinozako K, Matise T, And Preuss D. Nucleotide sequence database policies. Science. 2002;298:1331–1332. - PubMed
    1. Hunter S, Jones P, Mitchell A, Apweiler R, Attwood TK, Bateman A, Bernard T, Binns D, Bork P, Burge S, et al. InterPro in 2011: new developments in the family and domain prediction database. Nucleic Acids Res. 2012;40:D306–D312. - PMC - PubMed

Publication types