Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Oct;14(1-2):127-41.
doi: 10.1007/BF02795603.

Uptake and turnover of(65)Zn in subcellular fractions of brain of rat under normal and zinc-deficient conditions

J Wensink  1 , C H Paays, C J van den Hamer
Affiliations

Uptake and turnover of(65)Zn in subcellular fractions of brain of rat under normal and zinc-deficient conditions

J Wensink et al. Biol Trace Elem Res. 1987 Oct.

Abstract

After a single injection,(65)Zn is slowly taken up by the brain of the rat to a maximum after 7 d, followed by a turnover phase, with a half-time of about 3 wk. In the brain of rats on a zinc-deficient diet, the(65)Zn content in the brain continued to increase up to 30 d after the injection.The uptake and turnover phases in six different subcellular fractions of the brain showed a pattern similar to that of the whole brain in both the control and zinc-deficient rats. There was no internal redistribution of(65)Zn in the brain under conditions of progressive zinc deficiency.The results are discussed in a model for zinc homeostasis in the brain.

PubMed Disclaimer

References

    1. J Nutr. 1983 Oct;113(10):1895-905 - PubMed
    1. Clin Toxicol. 1981 Nov;18(11):1237-45 - PubMed
    1. Arch Neurol. 1975 Nov;32(11):745-51 - PubMed
    1. Biochem Pharmacol. 1961 Jul;7:88-95 - PubMed
    1. J Biol Chem. 1970 Sep 25;245(18):4724-31 - PubMed