The effects of the anaphylatoxins C3a and C5a on isolated mast cells from rat and man
- PMID: 2425572
- DOI: 10.1007/BF01988008
The effects of the anaphylatoxins C3a and C5a on isolated mast cells from rat and man
Abstract
Of the complement peptides comprising anaphylatoxin activity, only C5a caused a very small (less than 1.5%) but statistically significant histamine release from isolated human adenoidal mast cells. C3a and the respective des-Arg-derivatives were found to be ineffective. In rat peritoneal mast cells, neither peptide caused histamine release.
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