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Comparative Study
. 2013 Nov 20:14:327.
doi: 10.1186/1471-2474-14-327.

Independent associations of childhood and current socioeconomic status with risk of self-reported doctor-diagnosed arthritis in a family-medicine cohort of North-Carolinians

Antoine R Baldassari  1 , Rebecca J Cleveland, Leigh F Callahan
Affiliations
Comparative Study

Independent associations of childhood and current socioeconomic status with risk of self-reported doctor-diagnosed arthritis in a family-medicine cohort of North-Carolinians

Antoine R Baldassari et al. BMC Musculoskelet Disord. .

Abstract

Background: Associations of socioeconomic status (SES) with the prevalence of various forms of arthritis are well documented. Increasing evidence suggests that SES during childhood is a lasting determinant of health, but its association with the onset of arthritis remains unclear.

Methods: Cross-sectional data on 1276 participants originated from 22 family practices in North-Carolina, USA. We created 4-level (high, medium, low, lowest) current SES and childhood SES summary scores based on parental and participant education, occupation and homeownership. We investigated associations of individual SES characteristics, summary scores and SES trajectories (e.g. high/low) with self-reported arthritis in logistic regression models progressively adjusted for race and gender, age, then BMI, and clustered by family practice.

Results: We found evidence for independent associations of both childhood and current SES with the reporting of arthritis across our models. In covariate-adjusted models simultaneously including current and childhood SES, compared with high SES participants in the lowest childhood SES category (OR = 1.39 [95% CI = 1.04, 1.85]) and those in the low (OR = 1.66 [95% CI = 1.14, 2.42]) and lowest (OR = 2.08 [95% CI = 1.16, 3.74]) categories of current SES had significantly greater odds of having self-reported arthritis.

Conclusions: Current SES and childhood SES are both associated with the odds of reporting arthritis within this primary-care population, although the possibly superseding influence of existing circumstances must be noted. BMI was a likely mechanism in the association of childhood SES with arthritis onset, and research is needed to elucidate further pathways linking the socioeconomic environment across life-stages and the development of rheumatic diseases.

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Figure 1
Figure 1
Flowchart of participants from the NC-FM-RN into the current study.
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References

    1. Blagojevic M, Jinks C, Jeffery A, Jordan KP. Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage. 2010;14(1):24–33. - PubMed
    1. Brennan SL, Turrell G. Neighborhood disadvantage, individual-level socioeconomic position, and self-reported chronic arthritis: a cross-sectional multilevel study. Arthritis Care Res (Hoboken) 2012;14(5):721–728. - PubMed
    1. Callahan LF, Shreffler J, Mielenz T, Schoster B, Kaufman JS, Xiao C, Randolph R, Sloane PD. Arthritis in the family practice setting: associations with education and community poverty. Arthritis Rheum. 2008;14(7):1002–1008. - PubMed
    1. Callahan LF, Shreffler J, Siaton BC, Helmick CG, Schoster B, Schwartz TA, Chen JC, Renner JB, Jordan JM. Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a cross-sectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project. Arthritis Res Ther. 2010;14(2):R46. - PMC - PubMed
    1. Cleveland RJ, Schwartz TA, Prizer LP, Randolph R, Schoster B, Renner JB, Jordan JM, Callahan LF. Associations of educational attainment, occupation, and community poverty with hip osteoarthritis. Arthritis Care Res (Hoboken) 2013;14(6):954–961. - PMC - PubMed

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