doi: 10.1007/BF02989243.
Iron is maintained as Fe(II) under aerobic conditions in erythroid cells
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- PMID: 24264114
- DOI: 10.1007/BF02989243
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Iron is maintained as Fe(II) under aerobic conditions in erythroid cells
Biol Trace Elem Res.
1984 Aug.
Abstract
It was found that in rabbit erythrocytes loaded with Fe(II) (using the ionophore, A23187) over 90% of this metal is maintained in its ferrous form. In rabbit reticulocytes more than 50% of the transferrin-donated nonheme iron proved to be divalent. These results strongly suggest that under aerobic conditions the intracellular environment of intact erythroid cells is reducing for iron.
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