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Comment
. 2013 Dec;62(12):3990-2.
doi: 10.2337/db13-1314.

Following the fate of the failing β-cell: new insights from first-phase insulin responses

Alistair J K Williams  1 , Anna E Long
Affiliations
Comment

Following the fate of the failing β-cell: new insights from first-phase insulin responses

Alistair J K Williams et al. Diabetes. 2013 Dec.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Schematic showing potentially informative tests for tracking the loss of β-cell mass and function. Deterioration of FPIR in the IVGTT and of OGTT responses are currently the best indicators of impending diabetes. Imaging methods for monitoring β-cell mass are still in development. Little is known about the pattern of insulitis and decline in β-cell mass in humans during the prediabetic prodrome. PI/C-peptide, proinsulin-to-C-peptide ratio; Teff, effector T cells.
See this image and copyright information in PMC

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