Stem cells for periodontal regeneration
- PMID: 24265588
- PMCID: PMC3835291
- DOI: 10.2478/bjmg-2013-0012
Stem cells for periodontal regeneration
Abstract
Periodontal regeneration is considered to be biologically possible but clinically unpredictable. In periodontitis, inflammation manifests clinically as loss of supporting periodontal tissues and regeneration of damaged tissue is the main goal of treatment. For decades, periodontists have sought to repair the damage through a variety of surgical procedures, and use of grafting materials and growth factors, and of barrier membranes. Reports have emerged that demonstrate which populations of adult stem cells reside in the periodontal ligaments of humans and other animals. This opens the way for new cell-based therapies for periodontal regeneration. This review provides an overview of adult human stem cells and their potential use in periodontal regeneration.
Keywords: Periodontitis; Stem cells; Therapy.
Similar articles
-
Stem cells and periodontal regeneration.Aust Dent J. 2008 Jun;53(2):108-21. doi: 10.1111/j.1834-7819.2008.00019.x. Aust Dent J. 2008. PMID: 18494965 Review.
-
Cell- and Gene- Based Therapeutics for Periodontal Regeneration.Int J Prev Med. 2015 Nov 4;6:110. doi: 10.4103/2008-7802.169080. eCollection 2015. Int J Prev Med. 2015. PMID: 26682031 Free PMC article. Review.
-
Stem cell therapy: a challenge to periodontist.Indian J Dent Res. 2011 Jan-Feb;22(1):132-9. doi: 10.4103/0970-9290.79978. Indian J Dent Res. 2011. PMID: 21525691 Review.
-
Stem cell-delivery therapeutics for periodontal tissue regeneration.Biomaterials. 2012 Sep;33(27):6320-44. doi: 10.1016/j.biomaterials.2012.05.048. Epub 2012 Jun 12. Biomaterials. 2012. PMID: 22695066 Review.
-
Recent advances in the development of GTR/GBR membranes for periodontal regeneration--a materials perspective.Dent Mater. 2012 Jul;28(7):703-21. doi: 10.1016/j.dental.2012.04.022. Epub 2012 May 14. Dent Mater. 2012. PMID: 22592164 Review.
Cited by
-
Comparison of Cellular and Differentiation Characteristics of Mesenchymal Stem Cells Derived from Human Gingiva and Periodontal Ligament.J Int Soc Prev Community Dent. 2022 Apr 8;12(2):235-244. doi: 10.4103/jispcd.JISPCD_259_21. eCollection 2022 Mar-Apr. J Int Soc Prev Community Dent. 2022. PMID: 35462740 Free PMC article.
-
The Role of Angiogenesis and Pro-Angiogenic Exosomes in Regenerative Dentistry.Int J Mol Sci. 2019 Jan 18;20(2):406. doi: 10.3390/ijms20020406. Int J Mol Sci. 2019. PMID: 30669338 Free PMC article. Review.
-
Plants and Their Bioactive Constituents in Mesenchymal Stem Cell-Based Periodontal Regeneration: A Novel Prospective.Biomed Res Int. 2018 Aug 5;2018:7571363. doi: 10.1155/2018/7571363. eCollection 2018. Biomed Res Int. 2018. PMID: 30175141 Free PMC article. Review.
-
Efficacy of autologous stem cells for bone regeneration during endosseous dental implants insertion - A systematic review of human studies.J Oral Biol Craniofac Res. 2020 Oct-Dec;10(4):347-355. doi: 10.1016/j.jobcr.2020.06.007. Epub 2020 Jul 3. J Oral Biol Craniofac Res. 2020. PMID: 32714787 Free PMC article. Review.
-
Efficacy of stem cells on the healing of peri-implant defects: systematic review of preclinical studies.Clin Exp Dent Res. 2016 Feb 4;2(1):18-34. doi: 10.1002/cre2.16. eCollection 2016 Jun. Clin Exp Dent Res. 2016. PMID: 29744146 Free PMC article. Review.
References
-
- Albander JM . Epidemiology and risk factors of periodontal disease . Dent Clin North Am. 2005 ; 49 ( 3 ): 517 – 532 . - PubMed
-
- Slade GD , Spencer AJ , Roberts-Thomson KF . Australian dental generation: the national survey of adult oral health 2004–06. Australian Institute of Health and Welfare; Canberra: (available at: www.aihw.gov.au/WorkArea/DownloadAsset.aspx?id=10737421983).
-
- Bartold PM , McCulloch CA , Narayanan AS , Pitaru S . Tissue engineering: a new paradigm for periodontal re-generation based on molecular and cell biology . Periodontol 2000. 2000 ; 24 : 253 – 269 . - PubMed
-
- Sander L , Karring T . Healing of periodontal lesions in monkeys following the guided tissue regeneration procedure. A histological study . J Clin Periodontol. 1995 ; 22 ( 4 ): 332 – 337 . - PubMed
-
- Bartold PM , Narayanan AS . Periodontal regeneration . In: Bartold PM , Narayanan AS , editors. Biology of the Periodontal Connective Tissues. Chicago : Quintessence Publishing ; 1998 . pp. 60 – 73 .
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources