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Review
. 2014 Jan;98(1):73-85.
doi: 10.1016/j.mcna.2013.09.002. Epub 2013 Oct 20.

Cholestatic liver disease

Andrea A Gossard  1 , Jayant A Talwalkar
Affiliations
Review

Cholestatic liver disease

Andrea A Gossard et al. Med Clin North Am. 2014 Jan.

Abstract

The care of the patient with cholestasis hinges on identifying the etiology, treating reversible causes, and managing chronic cholestatic processes. PBC and PSC are important causes of chronic cholestasis, and are the most common causes of cholestatic liver disease. Effective therapy is available for patients with PBC, whereas none exists for patients with PSC. Awareness of the complications that may be associated with cholestasis and implementing the appropriate management are essential.

Keywords: Bile duct obstruction; Biliary tract disease; Cholestasis; Cholestatic liver disease; Primary biliary cirrhosis; Primary sclerosing cholangitis.

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