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. 2013 Dec;19(12):2028-30.
doi: 10.3201/eid1912.130614.

Hepatitis E virus variant in farmed mink, Denmark

Hepatitis E virus variant in farmed mink, Denmark

Jesper S Krog et al. Emerg Infect Dis. 2013 Dec.

Abstract

Hepatitis E virus (HEV) is a zoonotic virus for which pigs are the primary animal reservoir. To investigate whether HEV occurs in mink in Denmark, we screened feces and tissues from domestic and wild mink. Our finding of a novel HEV variant supports previous findings of HEV variants in a variety of species.

Keywords: Denmark; HEV; hepatitis; hepatitis E virus; mink; neovison vison; real time RT-PCR; viruses; zoonoses.

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Figures

Figure
Figure
Phylogenetic tree showing the relationship between the novel mink hepatitis E virus (HEV), other HEV variants, and the 4 known HEV genotypes based on 261 bp of the RdRp gene. The CLC Main Workbench software (CLC bio, Aarhus, Denmark) was used for the phylogenetic analysis. Alignments were made by using MUSCLE algorithm (www.drive5.com/muscle/) and phylogenetic tree was made by using distance-based method with the neighbor-joining algorithm and bootstrap value of 1,000. Phylogenetic analysis with other methods showed similar results. [Q: Scale bar indicates what?]

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