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. 2013 Dec;23(12):584-6.
doi: 10.1016/j.tcb.2013.09.009.

Of fish and men: using zebrafish to fight human diseases

Julien Ablain  1 , Leonard I Zon
Affiliations

Of fish and men: using zebrafish to fight human diseases

Julien Ablain et al. Trends Cell Biol. 2013 Dec.

Abstract

Long restricted to the field of developmental biology, the use of the zebrafish (Danio rerio) has extended to the study of human pathogenesis. Fostered by the rapid adaptation of new technologies, the design and analysis of fish models of human diseases have contributed important findings that are now making their way from aquariums to clinics. Here we outline the clinical relevance of the zebrafish as a model organism.

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Figures

Figure 1
Figure 1
Timeline of zebrafish studies and disease models. The black line represents the evolution of the number of publications on zebrafish per year between 1990 and 2012 (PubMed search). The selected zebrafish disease models discussed in the text are displayed in red. Other important models are mentioned in blue.
See this image and copyright information in PMC

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