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Review
. 2014 Feb;10(2):67-9.
doi: 10.1038/nrendo.2013.233. Epub 2013 Nov 26.

Puberty in 2013: Unravelling the mystery of puberty

Sergio R Ojeda  1 , Alejandro Lomniczi  1
Affiliations
Review

Puberty in 2013: Unravelling the mystery of puberty

Sergio R Ojeda et al. Nat Rev Endocrinol. 2014 Feb.

Abstract

In 2013, considerable progress was made towards deciphering the molecular foundations of puberty. Loss of transcriptional repression was identified as a core mechanism underlying the onset of puberty, and this loss was found to be precipitated by epigenetic cues. It was also discovered that nutritional deprivation delays puberty by repressing reproductive neuroendocrine function.

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