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Comment
. 2014 Feb;34(3):300-2.
doi: 10.1128/MCB.01519-13. Epub 2013 Nov 25.

FACT and the H2B N tail

Mary Ann Osley  1
Affiliations
Comment

FACT and the H2B N tail

Mary Ann Osley. Mol Cell Biol. 2014 Feb.

Abstract

The FACT histone chaperone/nucleosome reorganization factor plays key roles in nucleosome dynamics during transcription. A new study has linked a specific domain in the H2B N terminus to the activity of FACT in regulating nucleosome disassembly at promoters during transcription activation and nucleosome reassembly at coding regions during transcription elongation.

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References

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