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. 2013 Oct 31;3(4):55-7.
doi: 10.5826/dpc.0304a14. eCollection 2013.

Squamous cell carcinoma of the soft palate associated with autoantibodies to desmoglein 1 and 3

Yoshifumi Maumi  1 , Reiko Suzaki, Naoko Ito, Mizuki Sawada, Sumiko Ishizaki, Mariko Fujibayashi, Motohiko Aiba, Hiroyuki Kaneko, Masaru Tanaka
Affiliations

Squamous cell carcinoma of the soft palate associated with autoantibodies to desmoglein 1 and 3

Yoshifumi Maumi et al. Dermatol Pract Concept. .
No abstract available

Keywords: autoantibody; desmoglein; mucous membrane; soft palate; squamous cell carcinoma.

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Figures

Figure 1.
Figure 1.
Clinical finding: Erosive lesion measuring approximately 3 cm in diameter on the central part of the soft palate. [Copyright: ©2013 Maumi et al.]
Figure 2.
Figure 2.
Histopathological examination of hematoxylin-eosin stained tissue biopsy showed invasion of the lamina propria mucosa by tumor cells. Magnification, 20×. [Copyright: ©2013 Maumi et al.]
Figure 3.
Figure 3.
Histopathological examination of hematoxylin-eosin stained tissue biopsy under high magnification confirmed the diagnosis of undifferentiated squamous cell carcinoma. The subepithelial tissue shows marked inflammatory reaction with a mixture of lymphocytes and plasma cells. Magnification, 200×. [Copyright: ©2013 Maumi et al.]
Figure 4.
Figure 4.
Immunohistochemical staining for MIB1 (Ki67) showed nuclear staining in approximately 80% of tumor cells. Magnification, 200×. [Copyright: ©2013 Maumi et al.]
See this image and copyright information in PMC

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