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Case Reports
. 2013 Nov 28:2013:bcr2013201352.
doi: 10.1136/bcr-2013-201352.

Ocular quinine toxicity in a sleepwalker

Amit Sinha  1 , Sahar Al Husainy
Affiliations
Case Reports

Ocular quinine toxicity in a sleepwalker

Amit Sinha et al. BMJ Case Rep. .

Abstract

A 55-year-old woman presented to the emergency department following an episode of severe visual impairment, headache, dizziness and confusion. The patient had been taking quinine sulfate as long-term medication for leg cramps. During an episode of sleepwalking, the patient had taken an overdose of quinine sulfate. Following a thorough investigation and assessment, a diagnosis of ocular quinine toxicity was made. We present this case and highlight the risks of quinine prescription.

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Figures

Figure 1
Figure 1
Normal optical coherence tomography scan demonstrating human retina in cross section.
Figure 2
Figure 2
Optical coherence tomography scan demonstrating thinning of the inner plexiform layer and loss of ganglion cells.
See this image and copyright information in PMC

References

    1. Christoforidis J, Ricketts R, Loizos T, et al. Optical coherence tomography findings of quinine poisoning. Clin Ophthalmol 2011;5:75–80 - PMC - PubMed
    1. Brinton GS, Norton EW, Zahn JR, et al. Ocular quinine toxicity. Am J Ophthalmol 1980;90:403–10 - PubMed
    1. Mackie MA, Davidson J, Clarke J. Quinine-acute self-poisoning and ocular toxicity. Scott Med J 1997;42:8–9 - PubMed
    1. Prasad RS, Kodali VR, Khuraijam GS, et al. Acute confusion and blindness from quinine toxicity. Eur J Emerg Med 2003;10:353–6 - PubMed

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