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Review
. 2013 Nov 26;10(12):6292-304.
doi: 10.3390/ijerph10126292.

Foodborne Campylobacter: infections, metabolism, pathogenesis and reservoirs

Sharon V R Epps  1 , Roger B Harvey, Michael E Hume, Timothy D Phillips, Robin C Anderson, David J Nisbet
Affiliations
Review

Foodborne Campylobacter: infections, metabolism, pathogenesis and reservoirs

Sharon V R Epps et al. Int J Environ Res Public Health. .

Abstract

Campylobacter species are a leading cause of bacterial-derived foodborne illnesses worldwide. The emergence of this bacterial group as a significant causative agent of human disease and their propensity to carry antibiotic resistance elements that allows them to resist antibacterial therapy make them a serious public health threat. Campylobacter jejuni and Campylobacter coli are considered to be the most important enteropathogens of this genus and their ability to colonize and survive in a wide variety of animal species and habitats make them extremely difficult to control. This article reviews the historical and emerging importance of this bacterial group and addresses aspects of the human infections they cause, their metabolism and pathogenesis, and their natural reservoirs in order to address the need for appropriate food safety regulations and interventions.

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References

    1. Penner J.L. The Genus Campylobacter: A decade of progress. Clin. Microbiol. Rev. 1988;1:157–172. - PMC - PubMed
    1. Nachamkin I. Campylobacter and Archobacter. In: Murray P.R., Baron E.J., Jorgensen J.A., editors. Manual of Clinical Microbiology. 8th ed. American Society for Microbiology (ASM) Press; Washington DC.,USA: 2003. pp. 902–914.
    1. Parkhill J., Wren B.W., Mungall K., Ketley J.M., Churcher C., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M., van Vliet A.H., Whitehead S., Barrell B.G. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature. 2000;403:665–668. doi: 10.1038/35001088. - DOI - PubMed
    1. Gundogdu O., Bently S.D., Holden M.T., Parkhill J., Dorrell N., Wren B.W. Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence. BMC Genomics. 2007;8:471–472. doi: 10.1186/1471-2164-8-471. - DOI - PMC - PubMed
    1. Altekruse S.F., Stern N.J., Fields P.I., Swerdlow D.L. Campylobacter jejuni and emerging foodborne pathogen. Emerg. Infect. Dis. 1999;5:28–35. doi: 10.3201/eid0501.990104. - DOI - PMC - PubMed

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