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Review
. 2013:2013:720841.
doi: 10.1155/2013/720841. Epub 2013 Oct 30.

Surgical treatment of pediatric epileptic encephalopathies

J Fridley  1 , G Reddy, D Curry, S Agadi
Affiliations
Review

Surgical treatment of pediatric epileptic encephalopathies

J Fridley et al. Epilepsy Res Treat. 2013.

Abstract

Pediatric epileptiform encephalopathies are a group of neurologically devastating disorders related to uncontrolled ictal and interictal epileptic activity, with a poor prognosis. Despite the number of pharmacological options for treatment of epilepsy, many of these patients are drug resistant. For these patients with uncontrolled epilepsy, motor and/or neuropsychological deterioration is common. To prevent these secondary consequences, surgery is often considered as either a curative or a palliative option. Magnetic resonance imaging to look for epileptic lesions that may be surgically treated is an essential part of the workup for these patients. Many surgical procedures for the treatment of epileptiform encephalopathies have been reported in the literature. In this paper the evidence for these procedures for the treatment of pediatric epileptiform encephalopathies is reviewed.

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