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Editorial
. 2013 Dec 1;188(11):1275-7.
doi: 10.1164/rccm.201308-1500ED.

Chronic rhinosinusitis: the unrecognized epidemic

Bruce K Tan  1 , Robert C Kern, Robert P Schleimer, Brian S Schwartz
Affiliations
Editorial

Chronic rhinosinusitis: the unrecognized epidemic

Bruce K Tan et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

<i>Figure 1.</i>
Figure 1.
Application of a dynamic chronic episodic disease model to the natural history of chronic rhinosinusitis (CRS). Ordinary nasal and sinus symptoms progress through a transition through a state of rhinitis or acute rhinosinusitis (ARS) into CRS. In the model, CRS can be worsened by exacerbations of disease, durably remit at various points, or transition to recalcitrant CRS after exacerbations. Environmental, genetic, dietary, and developmental factors, the presence of comorbid diseases such as asthma, and specific microbial exposures, CRS phenotype, and surgical or medical management all likely affect transition rates to the various disease states.
See this image and copyright information in PMC

References

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