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. 2013 Dec;54(12):1127-32.

A retrospective study of non-suppurative encephalitis in beef cattle from western Canada

Sergio Sánchez  1 , Edward G Clark, Gary A Wobeser, Eugene D Janzen, Hélène Philibert
Affiliations

A retrospective study of non-suppurative encephalitis in beef cattle from western Canada

Sergio Sánchez et al. Can Vet J. 2013 Dec.

Abstract
in English, French

Non-suppurative encephalitis occurs sporadically in beef cattle in western Canada, leading to loss of animals. This retrospective study investigated the presence of viral, bacterial, and protozoal antigens or DNA in 37 western Canadian feedlot cattle with non-suppurative encephalitis for which a cause had not been identified. Cases were selected based on the age of the animal (> 7 months), and clinical history of recumbency and depression. The identification of rabies in 1 case stresses the importance of including this viral disease in the list of differential diagnoses. Because there was variation in the severity, distribution, and type of lesions, it is possible that there may be more than 1 cause, but failure to identify an infectious agent might also suggest that non-infectious agents could play a role.

Étude rétrospective de l’encéphalite non suppurative chez les bovins de boucherie de l’Ouest canadien. L’encéphalite non suppurative se produit sporadiquement chez les bovins de boucherie de l’Ouest canadien, ce qui cause une perte d’animaux. Cette étude rétrospective a fait enquête sur la présence d’antigènes viraux, bactériens et protozoaires ou d’ADN dans 37 parcs d’engraissement de l’Ouest canadien atteints de l’encéphalite non suppurative dont la cause n’avait pas été identifiée. Les cas ont été choisis en fonction de l’âge de l’animal (> 7 mois) et de l’anamnèse clinique de décubitus et de dépression. L’identification de la rage dans 1 cas met en lumière l’importance d’inclure cette maladie virale dans la liste des diagnostics différentiels. Parce qu’il y avait une variation au niveau de la gravité, de la répartition et du type de lésions, il est possible qu’il y ait plus d’une cause, mais la non-identification d’un agent infectieux pourrait aussi suggérer que des agents non infectieux pourraient jouer un rôle.(Traduit par Isabelle Vallières).

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Figures

Figure 1
Figure 1
A — Medulla oblongata showing severe mononuclear perivascular cuffing composed of lymphocytes, plasma cells and histiocytes. Hematoxylin and eosin (H&E). Bar = 20 μm. B — Medulla oblongata showing multifocal areas of gliosis. H&E. Bar = 50 μm. C — Midbrain with glial cells surrounding and phagocytizing a neuron (late stage of neuronophagia). H&E. Bar = 50 μm. D — Midbrain showing detection of rabies antigen in the perikaryon of neurons. Avidin-biotin complex peroxidase.1:400. Bar = 50 μm. E — Pons — Marked perivascular cuffing composed of lymphocytes, histiocytes, and few neutrophils. H&E. Bar = 20 μm. F — Pons — Multifocal vacuolation in the neuropil and scattered spheroids in the white matter. Scattered neutrophils, erythrocytes and microthrombi. H&E. Bar = 50 μm.
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