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Review
. 2013 Dec 2:8:195.
doi: 10.1186/1746-1596-8-195.

Primary solitary fibrous tumors of liver: a case report and literature review

Qiang Liu, Jing Liu  1 , Wenyou Chen, Shunbao Mao, Yihe Guo
Affiliations
Review

Primary solitary fibrous tumors of liver: a case report and literature review

Qiang Liu et al. Diagn Pathol. .

Abstract

A 42-year-old male presented right upper abdomen pain for more than 6 days, which misdiagnose calculus of intrahepatic duct and acute cholecystitis. An approximately 1.5 cm x 1.0 cm x 1.0 cm nodule was found and resected in left lateral lobe of hepatic. Pathological examination showed spindle cell and fibroblast -like cells within the collagenous stroma. Immunohistochemically, these spindle tumor cells showed diffuse Vim and Bcl-2 positive reactivity, but S-100 protein and HMB45 were negative. The post-operative course was uneventful. Solitary fibrous tumors of the liver, although rare, should be differentiated from mesenchymal lesions of the liver. Virtual slide: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/4214341041091088.

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Figures

Figure 1
Figure 1
Ultrasonography (US) revealed calculus of intrahepatic duct.
Figure 2
Figure 2
Magnetic resonance cholangiopancreatography(MRCP) revealed Gallbladdercalculi and cholecystitis and calculus of intrahepatic duct.
Figure 3
Figure 3
Gross appearance of the resected specimen, which measured 1.5 cm × 1.0 cm × 1.0 cm in left lateral lobe of hepatic.
Figure 4
Figure 4
Histologic features of the lesion showed the tumor was composed of small spindle cells, variably admixed with fiber texture (HE × 100).
Figure 5
Figure 5
Higher magnification showing fiber texture and spindle cells list storiform (HE × 400).
Figure 6
Figure 6
A clear demarcation between the tumor edge area and normal liver tissue (HE × 200).
Figure 7
Figure 7
The distribution of typical blood vessel in the normal liver tissue (HE × 200).
Figure 8
Figure 8
Tumor cells showing diffuse immunohistochemical positivity for CD-34.
Figure 9
Figure 9
Tumor cells showing diffuse immunohistochemical positivity for Bcl-2.
See this image and copyright information in PMC

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