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Review
. 2014 Feb;20(1):47-55.
doi: 10.1097/MCC.0000000000000048.

Biomarkers in acute respiratory distress syndrome

Alexandra Binnie  1 , Jennifer L Y Tsang, Claudia C dos Santos
Affiliations
Review

Biomarkers in acute respiratory distress syndrome

Alexandra Binnie et al. Curr Opin Crit Care. 2014 Feb.

Abstract

Purpose of review: The article provides an overview of efforts to identify and validate biomarkers in acute respiratory distress syndrome (ARDS) and a discussion of the challenges confronting researchers in this area.

Recent findings: Although various putative biomarkers have been investigated in ARDS, the data have been largely disappointing and the 'troponin' of ARDS remains elusive. Establishing a relationship between measurable biological processes and clinical outcomes is vital to advancing clinical trials in ARDS and expanding our arsenal of treatments for this complex syndrome.

Summary: This article summarizes the current status of ARDS biomarker research and provides a framework for future investigation.

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