doi: 10.1016/0014-4827(86)90180-1.
Preferential modulation of embryonic cell proliferation and differentiation by embryonic interferon
- PMID: 2429852
- DOI: 10.1016/0014-4827(86)90180-1
Item in Clipboard
Preferential modulation of embryonic cell proliferation and differentiation by embryonic interferon
Exp Cell Res.
1986 Dec.
Abstract
Embryonic-interferon (E-IFN), a novel species of interferon (IFN) produced solely by embryo cells, inhibited the proliferation of embryo cells in early gestation preferentially vis-à-vis fetal cells in late gestation but had little effect on the in vitro differentiation of embryonic pre-adipocytes to adipocytes. In contrast, mature-interferon (M-INF) did not exhibit this preferential inhibition of cell proliferation and did inhibit pre-adipocyte differentiation. These results suggest that the function of E-INF is different from that of M-IFN and that this function may involve modulation of the developmental process.
Similar articles
-
Interferon inhibits the conversion of 3T3-L1 mouse fibroblasts into adipocytes.Proc Natl Acad Sci U S A. 1980 Jul;77(7):4099-103. doi: 10.1073/pnas.77.7.4099. Proc Natl Acad Sci U S A. 1980. PMID: 6159626 Free PMC article.
-
The antiproliferative effects of interferon on murine embryonic cells.Proc Soc Exp Biol Med. 1979 Jan;160(1):46-9. doi: 10.3181/00379727-160-40385. Proc Soc Exp Biol Med. 1979. PMID: 419124 No abstract available.
-
Regulation of cell growth by interferon.Cancer Metastasis Rev. 1987;6(3):199-221. doi: 10.1007/BF00144264. Cancer Metastasis Rev. 1987. PMID: 2446790 Review.
-
Regulation of cell proliferation and differentiation by interferons.Biochem J. 1985 Mar 1;226(2):345-60. doi: 10.1042/bj2260345. Biochem J. 1985. PMID: 2581554 Free PMC article. Review. No abstract available.
-
Interferon-gamma and interleukin-1 beta inhibit adipoconversion in cultured rodent preadipocytes.J Cell Physiol. 1992 May;151(2):300-9. doi: 10.1002/jcp.1041510211. J Cell Physiol. 1992. PMID: 1572904
Cited by
-
Distribution of immunoreactive 2',5'-oligoadenylate synthetase in mouse reproductive organs.Anat Embryol (Berl). 1996 Oct;194(4):349-54. doi: 10.1007/BF00198536. Anat Embryol (Berl). 1996. PMID: 8896698
-
Role of interferons in cell differentiation and development.Cytotechnology. 1991 Feb;5(Suppl 1):152-7. doi: 10.1007/BF00736836. Cytotechnology. 1991. PMID: 22358982
-
Development of the interferon system. I. In chicken cells development in ovo continues on time in vitro.In Vitro Cell Dev Biol. 1990 Oct;26(10):997-1003. doi: 10.1007/BF02624475. In Vitro Cell Dev Biol. 1990. PMID: 1700777
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
