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Comment
. 2013 Dec 10;110(50):E4819.
doi: 10.1073/pnas.1317084110. Epub 2013 Dec 3.

Pomalidomide is teratogenic in rats and rabbits and can be neurotoxic in humans

Jerome B Zeldis  1 , Troy L Carter, Robert D Knight, Julia Hui
Affiliations
Comment

Pomalidomide is teratogenic in rats and rabbits and can be neurotoxic in humans

Jerome B Zeldis et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

Conflict of interest statement: The authors declare a conflict of interest (such as defined by PNAS policy). The authors work for Celgene Corporation that is currently marketing pomalidomide - the subject of the article in question.

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References

    1. Mahony C, et al. Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro. Proc Natl Acad Sci USA. 2013;110(31):12703–12708. - PMC - PubMed
    1. Revlimid (Lenalidomide; Package Insert). Summit, NJ: Celgene Corporation; 2005, revised 2013.
    1. Christian MS, et al. Evaluation of the developmental toxicity of lenalidomide in rabbits. Birth Defects Res B Dev Reprod Toxicol. 2007;80(3):188–207. - PubMed
    1. Pomalyst (Pomaliomide; US Package Insert). Summit, NJ: Celgene Corporation; February 8th, 2013.

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