Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Jun 16;1(3):128-33.
doi: 10.12998/wjcc.v1.i3.128.

Peripheral cemento-ossifying fibroma: A case report with review of literature

Amit Kumar Mishra  1 , Rahul Maru, Shrikant Vishnuprasad Dhodapkar, Gagan Jaiswal, Rajesh Kumar, Heena Punjabi
Affiliations
Case Reports

Peripheral cemento-ossifying fibroma: A case report with review of literature

Amit Kumar Mishra et al. World J Clin Cases. .

Abstract

Peripheral cemento-ossifying fibroma (PCOF) is a rare osteogenic neoplasm that ordinarily presents as an epulis-like growth. This is of a reactive rather than neoplastic nature and its pathogenesis is uncertain. PCOF predominantly affects adolescent and young adults with greatest prevalence around 28 years. We report here a rare clinical case of PCOF of the mandible, 1 cm mesiodistally and 1.5 cm occluso-gingivally in diameter, which caused difficulty in eating and speech, in a 42-year-old female patient. She was asymptomatic for 1 year and on follow-up for 6 mo post surgically showed gingival health and normal radioopacity of bone without any recurrence. Clinical, radiographic and histological characteristics are discussed and recommendations regarding differential diagnosis, treatment and follow up are provided. The controversial varied nomenclature and possible etiopathogenesis of PCOF are emphasized.

Keywords: Gingivectomy; Granuloma; Peripheral cemento-ossifying fibroma.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Lingual view of the lesion with smooth non-ulcerated surface and broad attachment base. A: The lesion with smooth non-ulcerated surface; B: Broad attachment base.
Figure 2
Figure 2
Non involvement of bone. A: Intra oral periapical radiograph; B: Maxillary occlusal radiograph; C: Ortho pantomo radiograph.
Figure 3
Figure 3
Excised tissue measuring 1.5 cm × 1 cm. A: Length 1.5 cm; B: Width 1 cm.
Figure 4
Figure 4
Interrupted sutures placed with 3-0 black braided silk.
Figure 5
Figure 5
The features were suggestive of “peripheral cemento-ossifying fibroma”. A: Histological picture showing long slender rete ridges and parakeratinized stratified squamous epithelium; B: Round to ovoid basophilic cementum-like calcifications [hematoxylin-eosin (HE) staining, × 10]; C: Basophilic globules of calcified mass along with osteoid tissue, round to ovoid basophilic cementum-like calcifications (HE staining, × 40).
Figure 6
Figure 6
Post operative photograph of surgical site showing satisfactory healing 30 d after surgery.
See this image and copyright information in PMC

References

    1. Bhaskar SN, Jacoway JR. Peripheral fibroma and peripheral fibroma with calcification: report of 376 cases. J Am Dent Assoc. 1966;73:1312–1320. - PubMed
    1. Eversole LR, Rovin S. Reactive lesions of the gingiva. J Oral Pathol. 1972;1:30–38. - PubMed
    1. Gardner DG. The peripheral odontogenic fibroma: an attempt at clarification. Oral Surg Oral Med Oral Pathol. 1982;54:40–48. - PubMed
    1. Martín-Granizo R, Sanchez-Cuellar A, Falahat F. Cemento-ossifying fibroma of the upper gingivae. Otolaryngol Head Neck Surg. 2000;122:775. - PubMed
    1. Waldron CA. Fibro-osseous lesions of the jaws. J Oral Maxillofac Surg. 1993;51:828–835. - PubMed

Publication types

LinkOut - more resources