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Comment
. 2013 Dec;20(12):1344-6.
doi: 10.1038/nsmb.2728.

Poly-combing the genome for RNA

Loyal A Goff  1 , John L Rinn
Affiliations
Comment

Poly-combing the genome for RNA

Loyal A Goff et al. Nat Struct Mol Biol. 2013 Dec.

Abstract

An unresolved question in mammalian epigenetic regulation is how ubiquitously expressed chromatin-modifying complexes such as Polycomb group complex 2 (PRC2) find their specific target sites across an intricate choreography of localization events in time and space. Two recent studies now provide critical new insights into an intriguing genome-wide role for RNA in PRC2 regulation.

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References

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