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Comparative Study
. 2014 Feb;140(2):265-9.
doi: 10.1007/s00432-013-1559-1. Epub 2013 Dec 5.

Clinicopathological characteristics and prognosis of mucinous breast carcinoma

Ming Zhang  1 , Xiao-Dan Teng, Xin-Xin Guo, Ji-Shuang Zhao, Zhi-Gao Li
Affiliations
Comparative Study

Clinicopathological characteristics and prognosis of mucinous breast carcinoma

Ming Zhang et al. J Cancer Res Clin Oncol. 2014 Feb.

Abstract

Purpose: The clinical features and prognosis of mucinous breast carcinoma (MBC) are unclear because of its rarity. The aim was to describe the clinicopathological features and prognosis of patients with MBC in comparison with nonmucinous breast carcinoma (NMBC). Furthermore, we described the biological behavior of pure mucinous breast carcinoma (PMBC) by comparing clinicopathological features and prognosis with mixed mucinous breast carcinoma (MMBC).

Methods: We reviewed the records of 5,872 consecutive patients diagnosed with breast carcinoma who were resected surgically from March 2003 to October 2010. Among them, 117 patients with MBC were compared to 5,575 patients with NMBC. Furthermore, 88 patients with PMBC were compared to 29 patients with MMBC.

Results: There were statistical differences in age, pN stage, ER level, and PR level between the patients with MBC and NMBC. There were statistical differences in pT stage and pN stage between the patients with PMBC and MMBC. The overall five-year survival of patients with MBC was 88.1 % as compared with 81.9 % for patients with NMBC. The overall five-year survival of patients with PMBC was 91.3 % as compared with 80.4 % for patients with MMBC. The overall five-year survival of patients with PMBC was 91.3 % as compared with 81.9 % for patients with NMBC.

Conclusions: PMBC tended to have a better prognosis in comparison with other types of breast carcinoma.

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Conflict of interest statement

We declare that we have no conflict of interest.

References

    1. Anan K, Mitsuyama S, Tamae K, Nishihara K, Iwashita T, Abe Y, Ihara T, Nakahara S, Katsumoto F, Toyoshima S (2001) Pathological features of mucinous carcinoma of the breast are favourable for breast-conserving therapy. Eur J Surg Oncol 27:459–463 - DOI - PubMed
    1. Andre S, Cunha F, Bernardo M, Meneses e Sousa J, Cortez F, Soares J (1995) Mucinous carcinoma of the breast: a pathologic study of 82 cases. J Surg Oncol 58:162–167 - DOI - PubMed
    1. Bae SY, Choi MY, Cho DH, Lee JE, Nam SJ, Yang JH (2011) Mucinous carcinoma of the breast in comparison with invasive ductal carcinoma: clinicopathologic characteristics and prognosis. J Breast Cancer 14:308–313 - DOI - PMC - PubMed
    1. Barkley CR, Ligibel JA, Wong JS, Lipsitz S, Smith BL, Golshan M (2008) Mucinous breast carcinoma: a large contemporary series. Am J Surg 196:549–551 - DOI - PubMed
    1. Di Saverio S, Gutierrez J, Avisar E (2008) A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma. Breast Cancer Res Treat 111:541–547 - DOI - PubMed

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