Classification of locoregional lymph nodes in medullary and papillary thyroid cancer
- PMID: 24306103
- DOI: 10.1007/s00423-013-1146-6
Classification of locoregional lymph nodes in medullary and papillary thyroid cancer
Abstract
Background: Among the various thyroid malignancies, medullary and papillary thyroid carcinomas are characterized by predominant locoregional lymph node metastases that may cause morbidity and affect patient survival. Although lymph node metastases are frequently detected, the optimal strategy aiming at the removal of all tumor tissues while minimizing the associated surgical morbidity remains a matter of debate.
Purpose: A uniform consented terminology and classification is a precondition in order to compare results of the surgical treatment of thyroid carcinomas. While the broad distinction between central and lateral lymph node groups is generally accepted, the exact boundaries of these neck regions vary significantly in the literature. Four different classification systems are currently used. The classification system of the American Head and Neck Society and the corresponding classification system of the Union for International Cancer Control (UICC) are based on observations of squamous cell carcinomas and appointed to needs of head and neck surgeons. The classification of the Japanese Society for Thyroid Diseases and the compartment classification acknowledge the distinctive pattern of metastasis in thyroid carcinomas.
Conclusions: Comparison of four existing classification systems reveals underlying different treatment concepts. The compartment system meets the necessities of thyroid carcinomas and is used worldwide in studies describing the results of lymph node dissection. Therefore, the German Association of Endocrine Surgery has recommended using the latter system in their recently updated guidelines on thyroid carcinoma.
Similar articles
-
Prognostic significance of extranodal extension of regional lymph node metastasis in papillary thyroid cancer.Head Neck. 2015 Sep;37(9):1336-43. doi: 10.1002/hed.23747. Epub 2014 Oct 29. Head Neck. 2015. PMID: 24821456
-
[Lateral skip metastases in papillary thyroid carcinoma].Chirurg. 2012 Jul;83(7):667-8. doi: 10.1007/s00104-012-2334-6. Chirurg. 2012. PMID: 22782175 German. No abstract available.
-
Establishing a prediction model for lateral neck lymph node metastasis in patients with papillary thyroid carcinoma.Sci Rep. 2018 Nov 26;8(1):17355. doi: 10.1038/s41598-018-35551-9. Sci Rep. 2018. PMID: 30478394 Free PMC article.
-
Surgical Management of Lymph Node Compartments in Papillary Thyroid Cancer.Surg Oncol Clin N Am. 2016 Jan;25(1):17-40. doi: 10.1016/j.soc.2015.08.013. Surg Oncol Clin N Am. 2016. PMID: 26610772 Review.
-
[Lymph node dissection in non-medullary differentiated thyroid carcinoma].Ann Chir. 2006 Jul-Aug;131(6-7):361-8. doi: 10.1016/j.anchir.2005.10.009. Epub 2005 Nov 9. Ann Chir. 2006. PMID: 16329987 Review. French.
Cited by
-
Tumor deposits in thyroid carcinomas.Medicine (Baltimore). 2024 Jul 19;103(29):e38952. doi: 10.1097/MD.0000000000038952. Medicine (Baltimore). 2024. PMID: 39029040 Free PMC article.
-
The European Society of Endocrine Surgeons perspective of thyroid cancer surgery: an evidence-based approach.Langenbecks Arch Surg. 2014 Feb;399(2):135-9. doi: 10.1007/s00423-013-1157-3. Epub 2014 Feb 7. Langenbecks Arch Surg. 2014. PMID: 24504672 No abstract available.
-
[Total thyroidectomy with lymph node dissection of the central compartment for node-positive, capsular invasive papillary thyroid cancer: video contribution].Chirurg. 2014 Oct;85(10):895-903. doi: 10.1007/s00104-014-2802-2. Chirurg. 2014. PMID: 25294049 German.
-
The advantages of extended subplatysmal dissection in thyroid surgery-the "mobile window" technique.Langenbecks Arch Surg. 2017 Mar;402(2):257-263. doi: 10.1007/s00423-016-1545-6. Epub 2017 Jan 3. Langenbecks Arch Surg. 2017. PMID: 28050728
References
Publication types
MeSH terms
Supplementary concepts
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical