Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Dec;64(6):521-4.
doi: 10.1016/0013-4694(86)90189-6.

Parkinson disease: electrophysiological (CNV) analysis related to pharmacological treatment

G Amabile, F Fattapposta, G Pozzessere, G Albani, L Sanarelli, P A Rizzo, C Morocutti

Parkinson disease: electrophysiological (CNV) analysis related to pharmacological treatment

G Amabile et al. Electroencephalogr Clin Neurophysiol. 1986 Dec.

Abstract

The contingent negative variation (CNV) was studied in a group of patients with Parkinson's disease. Testing was carried out 3 times: after a pharmacological wash-out period and at 15 and 30 days after the start of treatment with L-DOPA and bromocriptine. Peak and area CNV increased significantly after each treatment. The post-imperative negative variation (PINV) was observed in 6 out of 10 patients. The correlation found between electrophysiological functioning (CNV) measures and pharmacological treatment supports the view that dopaminergic brain activity mediates the generation of the slow negative event-related brain potentials.

PubMed Disclaimer

LinkOut - more resources