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. 1986 Dec;54(3):924-7.
doi: 10.1128/iai.54.3.924-927.1986.

Stability of expression of Neisseria gonorrhoeae lipooligosaccharides

H Schneider, C A Hammack, B A Shuman, J M Griffiss

Stability of expression of Neisseria gonorrhoeae lipooligosaccharides

H Schneider et al. Infect Immun. 1986 Dec.

Abstract

We compared multiple lipooligosaccharide (LOS) extracts from individual strains of Neisseria gonorrhoeae. Each of the extracts was prepared from single mass cultures grown on solid media under similar conditions but separated by time. We found only subtle variations in the number, electrophoretic mobility, and concentration of components of the LOSs from individual strains. We found no variation in the expression of a 3.6-kilodalton LOS component that carries the L8 LOS epitope. A significant variation in the 3-deoxy-D-manno-octulosonic acid content was found among different extracts from the same strain, but this variation appeared to be unrelated to the other LOS characteristics studied.

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