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. 2013:2013:692754.
doi: 10.1155/2013/692754. Epub 2013 Nov 7.

A case of recurrent mesocolon myxoid liposarcoma and review of the literature

Amar M Eltweri  1 , Gianpiero Gravante, Sarah Louise Read-Jones, Sonpreet Rai, David J Bowrey, Ian Gordon Haynes
Affiliations

A case of recurrent mesocolon myxoid liposarcoma and review of the literature

Amar M Eltweri et al. Case Rep Oncol Med. 2013.

Abstract

Background. Liposarcoma is the second most common soft tissue sarcoma affecting predominantly the retroperitoneal space and extremities. Mesenteric liposarcoma is uncommon and occurs in the small bowel mesentery. In this paper we report the case of a recurrent mesocolon myxoid liposarcoma manifesting 6 years from the initial right hemicolectomy for the primary tumour. Case Report. A 41-year-old female presented with a 4-day history of signs and symptoms indicative of small bowel obstruction, subsequently confirmed on plain abdominal X-ray. In 2006 she underwent a right hemicolectomy for a myxoid liposarcoma of the mesentery. The patient was initially managed conservatively; however she showed no signs of improvement and was taken to theatre for an exploratory laparotomy and division of adhesional bands. During this procedure an incidental finding of a dark purple, smooth pelvic mass was identified with similar macroscopic appearance to that of splenic tissue. Histological examination revealed a recurrent mesocolon myxoid liposarcoma. Conclusion. Mesocolon myxoid liposarcoma is a rare soft tissue neoplastic pathology and carries a high risk of recurrence. Therefore, a symptomatic patient with a previous history of primary liposarcoma excision should be treated with a high index of suspicion and a longer period of followup should be considered.

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Figures

Figure 1
Figure 1
Macroscopic appearance of the myxoid liposarcoma: a dark purple smooth mass measuring 12.5 × 11 × 6 cm that weighs 326 grams similar to splenic tissue. The black arrow indicates the stalk by which the liposarcoma was attached to the pelvic wall.
Figure 2
Figure 2
(a) Haemorrhagic infarcted tissue with background myxoid material and some viable cells identified at the periphery (haematoxylin-eosin, 10x). (b) Both lipoblasts and round cells at the periphery of the tumour (haematoxylin-eosin, 40x).
Figure 3
Figure 3
Frontal (left panel) and transverse (right panel) views of the CT scan performed postoperatively. A well-defined oval hypodense uniform mass is appreciated at the right iliac fossa measuring 10 × 8.4 cm with a central rounded higher density soft tissue area within it (white arrows).
See this image and copyright information in PMC

References

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