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Randomized Controlled Trial
. 2014 Jan-Feb;23(1):90-5.
doi: 10.1111/j.1521-0391.2013.12068.x. Epub 2013 Jun 26.

Associations between post-traumatic stress symptoms, stimulant use, and treatment outcomes: a secondary analysis of NIDA's Women and Trauma study

Lesia M Ruglass  1 , Denise A Hien, Mei-Chen Hu, Aimee N C Campbell
Affiliations
Randomized Controlled Trial

Associations between post-traumatic stress symptoms, stimulant use, and treatment outcomes: a secondary analysis of NIDA's Women and Trauma study

Lesia M Ruglass et al. Am J Addict. 2014 Jan-Feb.

Abstract

Background and objectives: To examine the associations between post-traumatic stress disorder (PTSD) symptoms, stimulant use, and treatment outcomes among dually diagnosed women.

Methods: Participants were 141 women who participated in a multisite clinical trial of group treatments for PTSD and addictions.

Results: Generalized linear models indicated Seeking Safety (SS; a cognitive-behavioral intervention) was significantly more effective than Women's Health Education (WHE; a control group intervention) in reducing stimulant use at follow-up among women who were heavy stimulant users at pre-treatment and who showed improvements in PTSD symptoms. There were no significant differences between the interventions among women who were light stimulant users at treatment entry.

Conclusions and scientific significance: These findings suggest that integrated treatment of co-occurring PTSD and addictions may be more effective than general health education approaches for heavy stimulant users. Assessment of frequency of stimulant use among individuals with PTSD symptoms may inform treatment selection for this population.

Trial registration: ClinicalTrials.gov NCT00078156.

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Conflict of interest statement

Conflict of Interest Disclosure:

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this paper.

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