Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2014 Jan-Feb;23(1):90-5.
doi: 10.1111/j.1521-0391.2013.12068.x. Epub 2013 Jun 26.

Associations between post-traumatic stress symptoms, stimulant use, and treatment outcomes: a secondary analysis of NIDA's Women and Trauma study

Lesia M Ruglass  1 , Denise A Hien, Mei-Chen Hu, Aimee N C Campbell
Affiliations
Randomized Controlled Trial

Associations between post-traumatic stress symptoms, stimulant use, and treatment outcomes: a secondary analysis of NIDA's Women and Trauma study

Lesia M Ruglass et al. Am J Addict. 2014 Jan-Feb.

Abstract

Background and objectives: To examine the associations between post-traumatic stress disorder (PTSD) symptoms, stimulant use, and treatment outcomes among dually diagnosed women.

Methods: Participants were 141 women who participated in a multisite clinical trial of group treatments for PTSD and addictions.

Results: Generalized linear models indicated Seeking Safety (SS; a cognitive-behavioral intervention) was significantly more effective than Women's Health Education (WHE; a control group intervention) in reducing stimulant use at follow-up among women who were heavy stimulant users at pre-treatment and who showed improvements in PTSD symptoms. There were no significant differences between the interventions among women who were light stimulant users at treatment entry.

Conclusions and scientific significance: These findings suggest that integrated treatment of co-occurring PTSD and addictions may be more effective than general health education approaches for heavy stimulant users. Assessment of frequency of stimulant use among individuals with PTSD symptoms may inform treatment selection for this population.

Trial registration: ClinicalTrials.gov NCT00078156.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosure:

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this paper.

References

    1. Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62:617–627. - PMC - PubMed
    1. Jacobsen LK, Southwick SM, Kosten TR. Substance use disorders in patients with posttraumatic stress disorder: A review of the literature. Am J of Psychiatry. 2001;158:1184–1190. - PubMed
    1. Brady KT, Back SE, Coffey SF. Substance abuse and posttraumatic stress disorder. Curr Dir Psychol Sci. 2004;13:206–209.
    1. Mills KL, Teesson M, Ross J, Peters L. Trauma, posttraumatic stress disorder, and substance use disorders: Findings from the Australian National Survey of Mental Health and Wellbeing. Am J of Psychiatry. 2006;168:651–658. - PubMed
    1. Najavits LM, Weiss RD, Shaw SR. A clinical profile of women with PTSD and substance dependence. Psychol Addict Behav. 1999;13:98–104.

Publication types

MeSH terms

Associated data