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Review
. 2013 Nov;24(4):703-15.
doi: 10.1016/j.pmr.2013.06.001. Epub 2013 Jul 23.

Co-occurring depression and pain in multiple sclerosis

Kevin N Alschuler  1 , Dawn M Ehde, Mark P Jensen
Affiliations
Review

Co-occurring depression and pain in multiple sclerosis

Kevin N Alschuler et al. Phys Med Rehabil Clin N Am. 2013 Nov.

Abstract

Depression and pain are highly prevalent among individuals with multiple sclerosis, and they often co-occur. The purpose of this article is to summarize the literature and theory related to the comorbidity of pain and depression and describe how their presence can impact individuals with multiple sclerosis. Additionally, the article discusses how existing treatments of pain and depression could be adapted to address shared mechanisms and overcome barriers to treatment utilization.

Keywords: Depression; Multiple sclerosis; Pain.

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References

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    1. O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: systematic review and proposed classification. Pain. 2008;137(1):96–111. - PubMed
    1. Alschuler KN, Ehde DM, Jensen MP. The co-occurrence of pain and depression in adults with multiple sclerosis. Rehabilitation Psychology. In press. - PMC - PubMed
    1. Alschuler KN, Jensen MP, Ehde DM. Defining mild, moderate, and severe pain in persons with multiple sclerosis. Pain Med. 2012;13(10):1358–65. - PMC - PubMed

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